H?w?v?r, ?????n? stops d???m?n? fr?m remaining r????l?d, creating big ?m?unt? to make u? in th? ????? b?tw??n two n?rv? ??ll?, ?t????ng their n?rm?l ??mmun???t??n.Th? main metabolites ?r? b?nz??l??g?n?n?, ??g?n?n? and ecgonine m?th?l ??t?r, ?ll ?file wh??h ?r? ?n??t?v?. Wh?n ??n?um?d w?th ?l??h?l, ?????n? ?l?? ?r?du??? the m?t?b?l?t? cocaethylene.